Life Science Events

This international interdisciplinary event is an open forum for discussion of current research and thinking regarding an organisms first line of defence. Using a multi-professional and inter-specialty approach this event promises plenty of opportunity for discussion and debate set in an informal atmosphere.

This event has CPD accreditation

Who Should Attend: Academic and biotechnology/biopharma research professionals interested in function and potency of immune response components against pathogens and tumours; also scientists interested in how understa nding these mechanisms can inform the design of biological therapeutics and their mechanisms of action , with translational implications for therapy.

Talks include

• Toll-like receptors in Helicobacter pylori infection & immunity:

Dr Sinead Smith, Ussher Assistant Professor, Dept. of Clinical Medicine, Dublin, Ireland

• Macrophage plasticity in normal and disturbed immunity: the key role of the switch macrophage phenotype:

Dr Igor Malyshev, Head of the Department of Pathophysiology, Moscow State University of Medicine and Dentistry, NJ, USA

• Role of novel macrophage derived mediators at regulating tissue repair and regeneration:

Dr Jesmond Dalli, Brigham’s and Women’s Hospital and Harvard Institute of Medicine, Boston Ma, USA

• Collagenous complement- activating pattern recognition molecules: sructure, mode of activation, and their involvement in antimicrobial defense and homeostasis:

Professor Jens Christian Jensenius , Department of Biomedicine, Aarhus University, Denmark, Germany.

• The role of microRNA and autophagy in innate immune responses to pathogens:

Dr Amal Amer, Associate Professor, Department of Microbial Infection and Immunity, Center for Microbial Interface Biology, Ohio State University

• Surfactant Protein A and D: To bind or not to bind?:

Dr Jens Madsen, Sir Henry Wellcome Laboratories, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK

• Heat-shock proteins in the regulation of inflammations:

Dr Gaetan Jego, Associate professor, University of Burgundy, France

• What influences susceptibility to and severity of infection with Clostridium difficile?:

Professor Christine Loscher, Immunomodulation Research Group, School of Biotechnology, Dublin City University, Ireland

• In vivo expansion of regulatory neutrophils with a GPCR19 agonist ameliorates systemic inflammation:

Dr SY Seong, Department of Microbiology and Immunology, Department of Biomedical Sciences, Seoul National University College of Medicine, Korea

• Novel HIV miRNA and chronic immune activation:

Dr Souvenir D Tachado, Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Boston, MA, USA

• Ocular surface innate immunity:

Dr Rachel Redfern, Assistant Professor, University of Houston, College of Optometry, Houston, Texas, USA

• Ocular Surface Innate Defence Mechanisms and How they are Compromised by Contact Lens Wear:

Professor Alison M McDermott, Golden-Golden Professor, Professor of Optometry and Vision Sciences, Professor of Biology and Biochemistry, The Ocular Surface Institute (TOSI), University of Houston, College of Optometry, TX, USA

• Potentiation of the CD8 antiviral activity (CAF) by Thymosin alpha1:new opportunities for immunomodulation during antiretroviral infections:

Dr Claudia Matteucci, University of Rome “Tor Vergata” , Rome, Italy

• Chemoattactant chemerin, a novel player in cutaneous defence:

Dr Joanna Cichy, Faculty of Biochemistry, Biophycics & Biotechnology, Jagiellonian University, Krakow, Poland

• Innate Immunity in Atherosclerosis:

Professor Alexander N. Orekhov, Institute of General Pathology and Pathophysiology, Director Institute for Atherosclerosis Research (Skolkovo), Moscow, Russia.

• Endocannabinoids are master regulatory bioactive lipids of Innate immunity-driven neuroinflammation:

Dr Valerio Chiurchiù, European Center for Brain Research (CERC), Laboratory of Neurochemistry of Lipids, IRCCS Fondazione S. Lucia, Rome, Italy

• A newly identified innate immune response to HIV infection:

Professor Áine McKnight, Professor of Viral Pathology, Queen Mary University of London, Blizard Institute, London, UK

• A Spaetzle-like role for Nerve Growth Factor b in vertebrate immunity to Staphylococcus aureus:

Dr R. Andres Floto, Cambridge Institute for Medical Research, University of Cambridge, UK

• New insights into the regulation of ILC2s – The enhancement and suppression of allergic lung inflammation:

Dr Grace Poon, University of British Columbia, Canada.

• Role of mast cells in innate immunity and autoinflammatory disorders:

Professor Andrew Craig, Department of Biomedical and Molecular Sciences, Queen’s University, Cancer Biology & Genetics division, Queen’s Cancer Research Institute, Canada.

• Tityus serrulatus venom induces inflammation dependent on TLRs recognition and inflammasome activation:

Dr Lucia Helena Faccioli, Universidade de São Paulo - Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Brazil

• TNFa influences on human NK responses:

Dr Karen E. Malone, Good Biomarker Sciences, Netherland

• Small molecule modulators of Toll-Like Receptor 4 (TLR4): a new generation of therapeutics:

Dr Francesco Peri, MSCA-ETN action, Horizon 2020 programme, Department of Biotechnology and Biosciences, University of Milano Bicocca, Italy

• Macrophages: The Origin and Purveyor of Immunity in Animals

Dr Charles D. Mills, Director, BioMedical Consultants, Croix, Minnesota United States

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