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Stem cells: from basic research to bioprocessing – 9th – 11th June 2015

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  • Confidently Assess Potential Unintended Binding and Activity of Biotherapeutics
    There is huge promise in harnessing the immune system, but misdirecting this powerful response can have serious consequences for patients. Even minimal off-target binding can lead to drug development failures, therefore rigorous specificity analysis is critical for success. Long believed to be highly specific, recent data indicate that antibodies frequently (~25%) display cross-reactivity. As a […]