Applications are invited for a Project Scientist to join the Laboratory of Dr Lindsay Hall (Wellcome Trust New Investigator) in Gut Health and Food Safety Programme at the Institute of Food Research.
This position will provide an exciting opportunity for a motivated individual to join a dynamic, multi-disciplinary research team investigating the early life (infant) microbiota and host interactions.
The Hall lab’s research focus involves defining the complex interactions of the host with the intestinal microbiota and pathogens at mucosal surfaces. More specifically the group is focussed on how members of the early life microbiota, including the genus Bifidobacterium, interact with the host including:
- how these pioneer bifidobacteria colonise the gut (including bacterial components and influence of diet)
- how microbiota members modulate immune function (including critical infection resistance and chronic inflammation)
- to understand how early life antibiotic-induced disturbances alter this microbial community, ultimately leading to a breakdown in pathogen protection and induction of inflammation
- to identify bifidobacterial communities and their components that can restore a disturbed early life microbiota back into one able to promote health
- to understand how probiotics can promote early life health in premature infants in Neonatal Intensive Care Units.
The Hall lab utilises multi-disciplinary approaches to answer these key questions including; microbiology (in vitro model-colon chemostat systems for complex culturing, molecular microbiology), metabolomics (NMR, MS), next generation sequencing (RNASeq, 16s rRNA, WGS, both host and microbe), bioinformatics tools, in vivo models (germ-free and infection models) and human studies (preterm/term infants).
The project takes place on the Norwich Research Park (including UEA, IFR, JIC and TGAC) which is the leading centre in UK in the study of the interactions of the gut microbiota and the host.
The goal of this Wellcome Trust funded position is to support ongoing lab activities including microbiota studies (clinical, in vitro and in vivo) and support new projects to identify ‘healthy’ early life microbiota signatures.
Applicants should have a background in biological research and ideally microbiology/microbiota studies and will act as a key member of the research group. A BSc or equivalent in biomedical science, or a related field is essential, as is outstanding personal initiative and communication skills.
This post is for a contract of 36 months.
For an informal discussion please contact Dr Lindsay Hall, Microbiome Research Leader (E-mail: Lindsay.Hall@ifr.ac.uk).
Details on how to apply can be found at http://jobs.ifr.ac.uk or contact Human Resources, Norwich BioScience Institutes Partnership, Norwich Bioscience Institutes, Norwich, NR4 7UA, UK, 01603 450149 quoting 1002943.
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The Institute of Food Research is a registered charity (No 1058499) and is an Equal Opportunities Employer.