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Postdoctoral position available in the laboratory of Dr. Simone Sanna-Cherchi in the Division of Nephrology at Columbia University Medical Center, New York.

The Laboratory

The Sanna-Cherchi lab is focused on understanding the genetic basis of kidney disease, with special emphasis on congenital malformation of the kidney and urinary tract and primary glomerulonephritis.

During the past 12 years Dr. Sanna-Cherchi established a network of investigators across more than 20 countries worldwide recruiting patients for genetic studies. His work spans the entire spectrum of genomics research. To complement his sequencing approaches for human traits, he has developed new mouse models for congenital defects of the urinary tract, and he is using zebrafish modeling to dissect genes within structural variants associated with developmental defects. His work provided a strong genetic link between pediatric kidney diseases and neurodevelopmental phenotypes, including autism, intellectual disability, schizophrenia, and others, with important repercussions beyond the field of nephrology.

His work has been published on the most prestigious journals, including the New England Journal of Medicine (2013), the Journal of Clinical Investigation (2015), the American Journal of Human Genetics (2007, 2012, 2015), the Journal of the American society of Nephrology (2005, 2009, 2014), Kidney International (2011, 2015) and many others (http://www.ncbi.nlm.nih.gov/pubmed/ term=sanna-cherchi+s ).

Dr. Sanna-Cherchi is well funded, with support from the National Institute of Health, the Department of Defense, the American Heart Association, and others; moreover, he has a strong track record for securing funding for his trainees (American Association of University Women, AAUW Fellowship; KNAW Ter Muelen Grant; Dutch Kidney Foundation Postodoctoral Fellowship; Italian Society of Nephrology Fellowship; American Society of Nephrology Postdoctoral Fellowship)

The candidate

We are looking for young and motivated researcher to train in a highly dynamic environment with exposure to world-leading investigators in the field of human genetics and developmental biology. The candidate will work on human genetics of pediatric kidney disease of broad medical relevance, by using novel state-of-the-art genomic tools to identify rare variants with large effect on the phenotype.

The candidate will have his own project and will have the opportunity to collaborate with other investigators in the lab working on large-scale genomic data and on functional modeling in vertebrates.

The qualified candidate should have:
1) a M.D. or Ph.D. degree (preferably in Genomics, Molecular genetics, Statistics, Bioinformatics, Computer Science, Physics, or a related field), and significant experience with large-scale genomic studies; 2) solid skills in at least one programming language (python, perl, R or C/C++); 3) practical experience in large-scale bioinformatics data analysis with familiarity to both microarray and next-generation sequencing data; 4) strong ability to communicate scientific material; 5) high enthusiasm, work ethics, and willingness to push the envelope.

Please Send Curriculum Vitae to: ss2517@cumc.columbia.edu

Columbia University is an Equal Opportunity/Affirmative Action employer —Race/Gender/Disability/Veteran.

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