The meeting will take place at The BioPark,
After our successful Bacteriophage Applications - current and potential applications in biotechnology, agriculture and medicine event which took place 16th May 2006 and Bacteriophages: Nature and Exploitation event which took place in 22 February 2008 we are delighted to announce our follow up event.
“Bacteriophages are the most abundant biological entities on earth and are major drivers of bacterial adaptive evolution. Studies on phage biology underpin our core knowledge of modern molecular biology - and phage research has provided many of the techniques and biochemical reagents used by all molecular biologists. This meeting is the third in a successful biennial series discussing the biological nature of bacteriophages, and their exploitation in basic microbiology (for genetics and functional genomics); diagnostics, ecology and evolution, phage display, vaccines, and in therapeutics in animal and human infections. The general structure of the meeting is to have short, expert presentations on this spectrum of topics, plus short Q&A sessions and offered posters. The meeting will be of interest to anyone who is currently using phages in their research work or who might be interested in the potential application of phages for basic biology, and applied topics such as bacterial diagnostics, vaccine development and phage therapy”. Meeting chair - Professor George Salmond,
This event will have a panel discussion session and you can submit your questions online during registration
On registration you will be able to submit your questions to the panel that will be asked by the chair on the day of the event
The agenda includes:
The nature and uses of bacteriophages: Professor George Salmond,
The link between pathogen evolution and bacteriophage. DrNicholas Thomson, Wellcome Trust Sanger Institute,
It is clear from genome sequencing that phage in recent times are probably the most significant source of variation for bacterial genomes. We have also seen that phage have had a long term impact on the virulence potential and evolution of many bacterial pathogens. Presented will be several case studies looking at the impact of phage on host variation and where we have used prophage to track the succession of different dominant Salmonella clinical isolates. Also described will be a study focussed on Citrobacter rodentium where phage have been significant in the evolution of this contemporary pathogen.
Phages from the sea: abundance and roles. Martha Clockie,
Stx-phages and virulence gene dissemination. Heather Allison,
Mechanism and application of phage integrases. Professor Maggie Smith,
Phage display technology and its applications . John McAfferty,
Exploiting phage technologies in the food industries. Dr Cath Rees,
Uses of phage in the animal food production chain. Professor Ian Connerton,
Acute wound infection control with bacteriophages. Dr Janice Spencer.
Phages immobilised by corona discharge technology onto sutures were used to secure an experimental wound. Wounds were infected with various concentrations of EMRSA 15 and the immobilised sutures used both to secure and close the wound. Control wounds showed little healing and clinical signs of infection whereas the phage coated sutures resulted in apparently normal healing. Histological examination confirmed the normal progress of the phage treated wounds. Microbiological examination showed some residual infection in all wounds, though less in phage treated wounds.
The Deadline for abstract submissions for oral presentation is November 10th 2009.
Abstracts for poster presentation only can be submitted up to two weeks before the event. Please note that there will be a best poster prize. All accepted abstracts will be published in the meeting proceedings
The Deadline for early registration is November 20th 2009. After this time the fees double, so make sure you register early!
If you would like to book a place at the meeting, please visit: www.regonline.co.uk/bacteriophage10
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