This event will discuss emerging research relating to the physiology, psychology and pharmacology of pain, and its assessment and management.
Chronic pain is a devastating health problem, and currently available treatments, including opioids and NSAIDS, often lack adequate efficacy leaving pain unrelieved. Tracey Ignatowski, PhD, (Assistant Professor of the Department of Pathology and Anatomical Sciences, Jacobs School of Medicine and Biomedical Sciences, The State University of New York at Buffalo), is the lead investigator of several studies demonstrating that heightened levels of the immune signalling protein, TNF-α, in the brain are a viable target for analgesia. Dr. Ignatowksi remarks, “Our understanding of the regulation of brain function and neuropathic pain by the immune system may be of fundamental importance to advancing our ability to provide new ways to help patients with intractable neurological disorders.”
While Professor Marino Convertino (University of North Carolina, USA) will discuss a unique signalling mechanism for opioid-dependent pain hypersensitivity. “The elucidation of this unique signalling mechanism provides a platform for the development of novel pharmacological strategies and/or therapeutic protocols involving the use of opiates and beta blockers.”
Dr Pippa Hawley (BC Cancer Agency, Vancouver, Canada) will talk about how the prognosis of patients receiving a cancer diagnosis has changed quite dramatically over the last few years, and that we have to think more about cancer as a chronic disease than ever before. “Non-opioid methods of cancer pain management need to be given a much higher priority in those with long life expectancies, and we as prescribers need to be much more alert to the emergence of addiction as a clinically relevant problem in 21st century cancer patients.”
Professor Graeme Jones (University of Tasmania, Hobart TAS, Australia) will review the evidence regarding pain in osteoarthritis and the implications for therapy. “Pain due to arthritis is extremely common in people aged over 50. Recent studies have shown that this pain has multiple causes. This, in turn, is leading to better treatment outcomes as therapies can be fine tuned so they best target the cause of the pain.”
While Dr. Luana Colloca, (University of Maryland School of Medicine, Baltimore, USA) will discuss placebo analgesia as a model to produce pain relief in individuals by virtue of expectations and anticipations of a benefit. Learned placebo analgesic effects can be elicited in patients suffering from pain disorders even when pain appears to be refractory to conventional pharmacological interventions .
Other talks include – Physical pain threshold and tolerance in self-harm (Dr. Olivia J. Kirtley, University of Glasgow, Glasgow, United Kingdom), Protective responses in pain: a closer look at perceptions of stiffness in chronic back pain (Dr. Tasha Stanton, University of South Australia) and Phantom limb pain in lower limb amputees (Dr Cliff Richardson, University of Manchester, UK).
Who Should Attend:This event is aimed at research scientists, physicians and pharmaceutical professionals working on both basic pain research and clinical aspects of pain, including pain management.
The event will be recorded and available for all registered delegates up to a month after the event. So if you can’t manage all the days, or the different time zones, you can still have access to the full event.
Invited speakers and their talks include:
|Central GABA-C receptors and anti-nociception||Professor Sastry Bhagavatula||The University of British Columbia||Canada|
|The use of animal models to elucidate the pathophysiology of "dysfunctional pain", an unexplained and formidable pain category||Dr. Yukinori Nagakura||Aomori University||Japan|
|Where does the pain come from in osteoarthritis?||Professor Graeme Jones||University of Tasmania||Australia|
|Morphine - P2Y12 inhibitors, a drug-drug interaction in STEMI patients||Professor Jacek Kubica||Nicolaus Copernicus University||Poland|
|The roles of Clathrin Heavy Chain-22 in human pain and touch development||Dr. Mike Nahorski||University of Cambridge||United Kingdom|
|Gonadal Hormones and Pain||Professor Anna Maria Aloisi||Università degli Studi di Siena||Italy|
|Novel morphine analogue 14-O-methylmorphine with high mu opioid receptor agonist efficacy, selectivity and affinity||Dr Ferenc Zádor||Hungarian Academy of Sciences||Hungary|
|Targeting mRNA translation regulation to alleviate nociceptor plasticity driving chronic pain||Dr. Theodore Price||University of Texas at Dallas||United States|
|Stancak, A. Brain electrophysiological representation of multidimensional subjective experience of pain during noxious laser heat stimulation||Dr. Andrej Stancak||University of Liverpool||United Kingdom|
|Role of 6TM-mOR and GPCR heterodimerization in opioid induced hyperalgesia||Dr. Marino Convertino||University of North Carolina||United States|
|What are the effects of therapeutic play intervention on children’s perioperative anxiety, negative emotional behaviour, and postoperative pain?||Dr. HE Hong-Gu||National University of Singapore||Singapore|
|TBC||Dr. Felipe Fregni||Harvard Medical School||United States|
|Conceptual framework of pain in persons with mild traumatic brain injury/concussion||Dr. Tatyana Mollayeva||University of Toronto||Canada|
|Clinical assesment of central sensitization in patients with musculoskeletal pain||Dr. Ramakrishnan Mani||University of Otago||New Zealand|
|Design of Novel Multivalent Ligands for the Treatment of Prolonged and Neuropathic Pain Without the Development of Addiction and Other Toxicities||Professor. Victor J. Hruby||University of Arizona||United States|
|Adapting the cancer pain management paradigm to non-cancer pain and survivorship||Dr. Pippa Hawley||BC Cancer Agency||Canada|
|Physical pain threshold and tolerance in self-harm: methodological challenges and future directions||Dr. Olivia J. Kirtley||University of Glasgow||United Kingdom|
|Chronic Pain Among Opioid Addiction Patients: Identifying and Managing an Important Risk Factor||Dr. Zainab Samaan||McMaster University||Canada|
|Decreasing Tumor Necrosis Factor-alpha Solely in the Brain for Treatment of Neuropathic Pain||Professor Tracey A. Ignatowski||University at Buffalo||United States|
|Challenges and success stories for Pain management in developing countries||Dr. Mary Ann Muckaden||Tata Memorial Centre||India
|Protective responses in pain: a closer look at perceptions of stiffness in chronic back pain||Dr. Tasha Stanton||The University of South Australia||Australia|
|Behavioural pain assessment tool development and the development and initial testing of a meta tool||Dr. Julie Gregory||University of Manchester||United Kingdom|
|TBC||Dr. Luana Colloca||University of Maryland School of Nursing University of Maryland School of Medicine||United States|
|Inpatient headache managament for migraines and chronic daily headaches||Dr. Priyanka Chaudhry||Baylor Comprehensive Headache Center||United States|
|Chronic Pain and Addiction: the Crossroads||Dr. Peter Przekop||Loma Linda University||United States|
|Where is pain in the brain||Professor Emeritus Amos D Korczyn||Tel Aviv University||Israel|
|Phantom limb pain in lower limb amputees: a discussion of the potential mechanisms||Dr. Cliff Richardson||University of Manchester||United Kingdom|
|The impact of baroreflex sensitivity for the treatment of chronic pain||Dr. Kati Thieme||Philipps-University of Marburg||Germany|
|Disconnecting pain - neurosurgical treatments for intractable oncological pain||Dr. Ido Strauss||Tel Aviv University||Israel|
|Gentian Violet: A Potential Treatment For Cutaneous Leishmaniasis||Dr Marc Karam||University of Balamand||Lebanon|
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