Postdoctoral Training Fellow


Postdoctoral Training Fellow
Stress & Metabolism
This is a full-time, fixed term (4 years) position on Crick Terms and Conditions of Employment.

Salary is competitive plus benefits, subject to skills and experience.

Scientific research area: Metabolic adaptations to stresses during development

A postdoctoral research post in the lab of Alex Gould is available. The postholder will use Drosophila and/or mouse models to identify new metabolic adaptations for coping with environmental stresses of various types during early life. This research builds upon other work that has identified several mechanisms protecting neural stem cells from starvation and oxidative stress. The successful applicants will use a wide range of techniques such as genetics, physiology, metabolomics, molecular biology and biochemistry.
For more information on this research, please visit the external lab website:

This role will be pivotal in ensuring the future success of the Crick’s research portfolio on metabolism in health and disease. The postholders will work in the laboratory of Alex Gould and report to him as line manager. Two-way scientific interactions will occur between the postholder and other members of the Gould group as well as with other laboratories at the Crick, including those using mouse models and the other four Drosophila groups, who share meetings once per week.

Objectives & responsibilities
The purpose of this Postdoctoral Training Fellow post is to implement an effective research programme on metabolic adaptations to stresses during development.

Specific objectives will include, but not be limited to:

• To conduct a programme of original research. The postholder will conduct efficiently, and at the level appropriate for a postdoctoral fellow, original research on metabolic adaptations to stresses during development in Drosophila.

• To prepare manuscripts, peer review and present research findings to a wider audience. The postholder will regularly attend and participate at scientific meetings with Alex Gould and with the several larger interest groups and forums at the Crick. They will actively participate in writing manuscripts, presenting work at national and international conferences and assisting Alex Gould in reviewing manuscripts and grant applications.

• To work collaboratively. The postholder will advise other members of the laboratory on techniques and, where appropriate, engage in collaborations with other members of the Gould laboratory and with other laboratories within and outside the Crick.

Key responsibilities:

• The post-holders will have day-to-day responsibility for running their research project. The general long-term direction of the research will be coordinated with the group leader, Alex Gould.

• The post-holders will take part in advising other members of the group, such as PhD students, summer students, and new postdoctoral fellows by providing scientific advice and technical guidance.

• It is mandatory that the post-holders will attend group meetings. They will provide scientific suggestions and other input into the ongoing research of other members in the lab.

Person Specification
The post holder should embody and demonstrate our core Crick values: Bold, Imaginative, Open, Dynamic and Collegial, in addition to the following:


• Ph.D in genetics, biochemistry, cell biology, chemistry, physiology or metabolomics (or in the final stages of completion).
• At least 3 years of bench experience in a laboratory but no postdoctoral experience is necessary
• Good communication/organisational skills


• Ph.D in Drosophila developmental biology or metabolism.
• High-quality refereed publications as a demonstration of productivity.
• Evidence for creativity and ability to think from first principles.

The Francis Crick institute (the Crick) is a partnership between the Medical Research Council (MRC), Cancer Research UK (CRUK), the Wellcome Trust, University College London (UCL), Imperial College London and Kings College London. It is a registered charity whose purpose is to conduct biomedical research into all aspects of human health and disease.

The Institute will be a world-leading centre of biomedical research and innovation. It will promote connections between researchers and disciplines and between academic institutions, healthcare organisations and businesses. Dedicated to research excellence, the institute will have the scale, vision and expertise to tackle the most challenging scientific questions underpinning health and disease. It will be world-class with a strong national role — training scientists and developing ideas for public good. On 1 April 2015, staff from the London Research Institute (CRUK) and National Institute for Medical Research (MRC) transferred to the Crick to form a fully functional research institute on four sites. In 2016, the Crick will move to a single new, purpose built research centre in St. Pancras which will house some 1,500 staff.

If you are interested in applying for this role please apply through our online system:

For any questions relating to this role, please contact either Alex Gould via or

REF: 428

Source: Nature Jobs

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