Friday, June 16, 2006 - 9:30 am - 4:30 pm   (GMT)
 
Birkbeck College 
Basement Lecture Theatre 
43 Gordon Square  
London,   WC1H 0PD  
United Kingdom 


Click here to find out more

 

Meeting Highlights
Towards the bigger picture  using Reactome to interpret high throughout data
Dr Imre Vastrik - EMBL - European Bioinformatics Institute, Cambridge
Life on the molecular level is an intricate network of biochemical reactions and pathways. Biologists have been elucidating fragments of the reaction network for a century. This information is stored as primary literature, review articles, textbooks, electronic databases and human memories, but remains largely inaccessible to computational investigation. The inability to manipulate this knowledge computationally is most keenly felt in the analysis of high throughput data. 
This presentation introduces Reactome  a knowledgebase of human biological processes  which captures biological knowledge in a computationally accessible manner.

Printing protein arrays from DNA arrays
Dr. Farid Khan,
Babraham Institute, UK
We have developed a novel system which enables the production of protein arrays directly from immobilised DNA arrays. In this method, cell-free protein synthesis is performed between two solid surfaces; one of which is arrayed with DNA molecules while the other surface carries a specific reagent to capture the translated proteins. Individual proteins are synthesised in parallel from the arrayed DNA and subsequently immobilised through interaction with the protein-capturing reagent on the opposite surface to form a protein array. This technology permits the generation of ‘pure’ protein arrays on demand in a single reaction. It also allows production of multiple copies of a protein array through the repeated use of a single DNA array template

Optimisation of DNA Microarrays
Mr Ben Jackson - Bio-Rad Lab Ltd

Genomics to Epigenomics: Ribosomal RNA Genes as a Paradigm between Form and Function
Dr Numo Neves - Universidade Nova de Lisboa, Portugal

Exploring protein-DNA binding specificities using microarrays
Dr. Ioannis Ragoussis
- Wellcome Trust Centre for Human Genetics - Oxford University

 

Assigning gene function - novel technologies and high throughput