Click here to find out more Meeting Highlights The Diversity of Neural Stem Cells - Professor Jack Price - MRC Centre for Neurodegeneration Research, Institute of Psychiatry, London. Neural Stem Cells can be isolated from Adult or Fetal brain, or derived from embryonic stem cells. Though these different sources of cells share seminal stem cell properties, they differ in other aspects of their phenotype. Importantly, some of these isolates have the capacity to repair the damaged nervous system, for others this is less certain. How are we to view this diversity of neural stem cell populations? In this talk, I will present our attempts to correlate cell and molecular phenotypes, and to understand the mechanisms that drive neural stem cell diversity.
The finding of a cell within skin that is capable of entering the myogenic lineage under certain conditions prompted us to identify a candidate factor for this conversion. Having identified the factor as galectin-1 we have gone on to determine the importance of galectin-1 in muscle determination and differentiation and how it could enhance muscle repair and regeneration following trauma and disease. Since these initial experiments we have begun to dissect out the role of galectin-1 in muscle and start to determine how it could be used to convert undifferentiated cells to the myogenic lineage thereby finding a therapeutic use for the molecule in enhancing myogenesis. Complexity of the Human Haematopoietic Stem Cell compartment - Dr Daniel Pearce -Cancer Research, UK The mammalian haematopoietic system is organised as a hierarchy where the majority of the cells are mature, and therefore, need to be continuously replenished from a small pool of immature progenitors. Ultimately, the entire haematopoietic system is derived from stem cells that have extensive proliferative and differentiation capacity and give rise to all myeloid and lymphoid lineages. Stem cells also have extensive ability to self-renew and are able to engraft recipients for long periods of time after transplantation. Progress in characterising human stem cells has been impaired by their rarity in normal haematopoietic tissue and the absence of a distinctive phenotype and functional repopulation assay. The engraftment of normal human haematopoietic cells in immune-deficient mice provides a system to develop an assay that measures the repopulating capacity of human stem cells and has allow the identification of a complexity of the stem cell compartment which will be discussed during the presentation in more details.Identification and isolation of Human Mesenchymal Stem Cells- Dr. Elena Jones - Leeds University Phenotypic and
Functional Characterization of Mouse Mammary Epithelial Stem Cells -
Dr John Stingl - Stemcell Technologies Inc Isolation, characterization and use of human AC133+ progenitor cells for vascular tissue repair - Dr Pauliina
Lehtolainen, Talk includes isolation, characterisation and knowledge of AC133+ cells and their lineage commitment towards endothelial cells and in vivo experience of their usage in tissue repair.
Identification,
Isolation and Expansion of Adult Stem
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Identification, Isolation and Expansion of Adult Stem Cells -12th May 2006, London, UK
Friday, May 12, 2006 - 9:15 am - 4:30 pm
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"Thanks for a delightful and interesting meeting. I think it worked just great with the mix of academic and company-based presentations and the whole program felt comprehensive and important" - Fredrik Ponten, MD, PhD Department of Genetics and Pathology, Uppsala University, HPR research group, Sweden "A big thanks to you and all your team for putting on the excellent meeting yesterday. The meeting place was great, and the organisation was superb. No hitches at all from my point of view. From the conversations I had with some of the delegates, it seems that the meeting was well received. There really is no other regular forum for these kinds of discussions in the UK , so it was a very welcome opportunity".- Prof. Julian Ma , Hotung Chair of Molecular Immunology, Dept. of Cellular and Molecular Medicine (CMM), St. George 's Hospital Medical School, London "A civilised exchange of views on differences in findings – clear presentations" - Jan Clark, CIMR "Liked the fact the speakers were available to answer questions during the coffee time. It was useful having the companies give seminars as opposed to just having them at their stand"- Sarah Burl, Infant Immunology Group, Virology Department, MRC The Gambia "Thoroughly enjoyed the meeting last week - just such a shame that I could not stay for the whole day - but what I did hear was very interesting. I certainly will come to more of the events as some of the titles on the programme look really good" - Professor Diana Watt, Professor of Human Anatomy, Brighton and Sussex Medical School, UK "We enjoyed the day very much indeed and look forward to attending another event soon".- Scott Reid. IAH Pirbright, Institute for Animal Health "Good location, staff very helpful, Tony Warford entertaining and knowledgeable chairman" - Pauline Connor, North Middlesex Hospital , London "Thank you for organising such a useful meeting. I know that it was apprecaited by many colleagues and that it provoked good discussion and scientific debate" - Dr Paul Duprex, School of Biomedical Sciences, The Queen's University of Belfast, Ireland "Well organised, interesting speakers were chosen" - Philippa Roddam, St Jude Children's Research Hospital , Memphis, USA "Very high quality talks and speakers"- Joanna Bridger PhD, Senior L ec turer, Centre for Cell and Chromosome Biology, Biosciences, Brunel University "I enjoyed the meeting, the duration of each of the speakers was just right and was pitched at just the right level for the audience. Great forum for meeting people and discussing the subject matter, overall very informative" - Vivien Jacobs, AstraZenea "I have found the talks very stimulating. The content was of high standard . A well run and presented meeting ".- Mrs Jean Bettany, Smith & Nephew, UK "Good range of talks – very interesting and relevant" - Dr Lorna Jarvis , Addenbrooke's Hospital, Cambridge, UK "James was pleased and said the meeting was excellent, with lots of discussion. I would be delighted to participate in the next edition". - Lorenzo Frigerio, Department of Biological Sciences, University of Warwick " Thank you very much for the invitation to speak last Friday. I found the meeting interesting, useful and enjoyable. Well done to the organisers" . Paula Murphy B. A .(mod), PhD., Lecturer, Zoology Department, Trinity College Dublin, Ireland " Very much enjoyed the event - would definitely speak at a future EuroSciCon event if asked again". Chris Mason MB BS, PhD FRCS, Regenerative Medicine Bioprocessing Uni, Advanced Centre for Biochemical Engineering, University College, London " It was an enjoyable meeting, and as someone starting out in the proteomics field on a new collaborative grant very informative" . Peter J Charles, Chief Biomedical Scientist, Division of Immunology, Hammersmith Hospitals NHS Trust "The very informal setting enabled lively discussion in refreshment breaks" - Louise Jopling, UCB Group "Very well organised, friendly staff, good quality talks" - Professor John A Bryant, Chair, Christians in Science, School of Biosciences , University of Exeter "I found the meeting 'Visualising transcription, gene positioning and reorganisation in the nucleus' very very interesting. I'll keep into real consideration to came back to your next meetings" - Dr. MariaPaola Recalcati, Istituto A uxologico Italiano, Milan, Italy 'It was a very good meeting for Guava and I look forward to joining a few more in the future'. - Dr Paul Wheeler, UK Sales Manager, Guava Technologies Inc. "It is good to go to a relatively small meeting that is easy to go to and is good value for money. I think the mix between industry and academics is very good". - Prof W Ollier, Manchester University, CIGMR "A good selection of speakers and interesting subject matter " - Andrew Jefferson, Molec ular Cytogenetics and Microscopy, Wellcome Trust Center for Human Genetics, UK
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