Posts Tagged ‘ Dendritic cells; tolerance; autoimmunity; cancer; vaccine ’

Inducing and Breaking Tolerogenic Antigen-Presenting Cell Function - 05 July 2012

Antigen Presenting Cells

Professional antigen-presenting cells (APC) such as dendritic cells (DC) and macrophages play a critical role in the initiation and maintenance of a T cell-mediated immune response. APC are essential for T cell priming, differentiation and activation in lymphoid tissue and at sites of inflammation. Understanding the molecular mechanisms via which APC function can be...

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