"cell apoptosis" "cell engineering" "induced pluoripotency" "recombinant protein production" 3D cell culture 3D culture Autophagy batch to batch consistency bioprocessing conference bioreactor cell cell contamination cell culture cell culture conference cell therapy cell transformation cGMP cho cells clinical grade cold-shock cornea eye ferrets Flux genomic imprinting human embryonic stem cells incubation Influenza large scale lasers limbal epithelial stem cells mammalian cell culture media Media Development microscopy multiplexing organ culture p62 pigs pluripotency Process Development Puncta recombinant protein production; cold-shock; CHO cells; cell engineering respiratory tract Soluble proteins transfection upstream processes Vaccines