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The meeting will be held at The BioPark, Hertfordshire, UK and has CPD approval. The Chair will be Professor Michael J. Day BSc BVMS(Hons) PhD Dipl ECVP FASM FRCPath FRCVS, University of Bristol, UK. The Deadline for early registration is August 20th 2009. After this time the fees double, so make sure you register early!
The Agenda includes: Identification of the major allergens in saliva of Culicoides nubeculosus (biting midge). - Dr Doug Wilson, University of Bristol, UK. Insect bite hypersensitivity (IBH) is an allergy of horses to the bites of midges [Culicoides spp.]. Affected horses develop an acute phase response following intradermal challenge with Culicoides salivary gland proteins followed by a late phase response in which skin biopsies show increased numbers of infiltrating T-cells, mast cells, eosinophils and IgE producing B-cells. Symptoms include pruritis, hair loss, serous effusion and haemorrhage followed by a chronic dermal fibrosis, and hyperkeratosis. Current research has focused on identifying the abundant salivary gland proteins of Culicoides that act as allergens; with a long term goal of developing an effective immunotherapy for this condition.
Insect bite hypersensitivity in Iceland horses - Dr Elaine Marti, University of Bern, Switzerland
Genetics of Canine Atopic Dermatitis: A Suitable Model for the Human Condition? - Shona Wood, Faculty of Veterinary Sciences, The University of Liverpool, UK
The use of canines as a model for human disease is advantageous because different breeds form genetically isolated populations in strong linkage disequilibrium. This is of benefit in genetic study because less genetic markers are required to find an association with the disease and smaller sample sizes can be used to find these associations, relative to human genetic studies. My work has focused on the identification of the genetic factors causing cAD. By using mRNA expression microarray, qPCR validation and literature searches candidate genes for cAD have been identified. Moreover a whole genome scan was performed using the Illumina SNP chip to identify potentially causative SNPs. These data informed a large scale case/control comparison of SNP frequencies using the Sequenom platform. I will discuss the results of this study in terms of the similarities with the human condition and the use of the dog as a disease model for humans.
The pathogenesis of canine atopic dermatitis - Dr Tim Nuttall, The University of Liverpool, UK. Canine atopic dermatitis (AD) is a common inflammatory dermatosis with a complex pathogenesis. It is possible that epidermal barrier defects enhance exposure to allergens, irritants and micro-organisms. Most cases possess IgE to environmental allergens (10-20% of cases appear to be non-allergic), which bind to FcεRI on Langerhans cells, enhancing allergen capture, and mast cells, mediating activation. Acute lesions are dominated by TH2-type chemokines and cytokines that recruit and activate eosinophils and other cells. Subsequent self-trauma, keratinocyte activation and microbial colonisation induce TH1-mediated chronic cell-mediated inflammation. Failure of T-regulatory cell mechanisms may prevent resolution.
Talk Title to be confirmed - Dr Petra Roosje, University of Bern, Switzerland
Mechanisms of allergy and their diagnostic relevance - Dr Carsten B. Schmidt-Weber, Imperial College, London, UK. Allergy disease are caused by immunologic allergen tolerance. Recent developments in the understanding of the immune system dramatically changed our view on the cause of this loss of immune tolerance. Consequently diagnosis of this immunologic disease requires more comprehensive approaches.
The Deadline for abstract submissions is August 10th 2009.Abstracts will be accepted for poster and oral presentation and there will be a best poster prize. All accepted abstracts will be published in the *meeting proceedings If you would like to book a place, please visit : www.regonline.co.uk/OneMedicine09 | |||
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One Medicine: Comparative Aspects of Research and Clinical Diagnosis in Allergic Disease - 20th November 2009.
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"It was a pleasure to chair the meeting, I am not just paying lip service either, the delegates were very enthusiastic, in fact we put an impromptu sessions on nanoparticles into the lunch time break, this was a request generated by the delegates, so I was very impressed, it was very well organised and I felt my time was very well spent" - Ian Dimmick, Flow Cytometry Core Facility Manager, Newcastle University, UK "Many thanks for your email and delegate list - it was a most enjoyable and informative meeting" Professor John Gallagher, The Paterson Institute for Cancer Research, Manchester, UK "It was an interesting event indeed with some follow up for my group - a possible collaboration.….I did enjoy the meeting very much"- Dr NinoPorakishvili, University of Westminster, UK "Thank you for giving me the opportunity to speak at your meeting yesterday. It was a very interesting meeting and provided a great opportunity to exchange ideas among investigators in the innate immunity/TLR field". Dr Michael Carty, Trinity College Dublin "I thoroughly enjoyed the meeting". Professor Neil Gow, University of Aberdeen , UK " It was jolly good meeting/ Look forward to recieving the proceedings and also the e-mails and addresses of the participants. This meeting aroused my old itchings for revisiting some unfinished science". Professor PK Das, University of Amsterdam, Holland "I thought the lecture theatre was superb and the organisation was top notch." Steven Jones, DakoCytomation Ltd, UK "Thanks for a delightful and interesting meeting. I think it worked just great with the mix of academic and company-based presentations and the whole program felt comprehensive and important" - Fredrik Ponten, MD, PhD Department of Genetics and Pathology, Uppsala University, HPR research group, Sweden "I enjoyed the scientific aspects of the conference also the opportunity of meeting so many delegates in our field" Professor Ten Feizi, Director, Glycosciences Laboratory, Imperial College London, UK "Thank you for the opportunity to speak, which I hope was interesting for the majority of the audience. I would like to say that the organistion of the event was excellent" Andy Sutcliffe, Procognia Ltd,UK "A big thanks to you and all your team for putting on the excellent meeting yesterday. The meeting place was great, and the organisation was superb. No hitches at all from my point of view. From the conversations I had with some of the delegates, it seems that the meeting was well received. There really is no other regular forum for these kinds of discussions in the UK , so it was a very welcome opportunity".- Professor. Julian Ma , Hotung Chair of Molecular Immunology, Dept. of Cellular and Molecular Medicine (CMM), St. George 's Hospital Medical School, London "A civilised exchange of views on differences in findings – clear presentations" - Jan Clark, CIMR "I thought the day was successful. I would be interested in doing something similar again" Kind regards Professor Andrew Peters - Director of ARPEXAS Ltd, University of Nottingham, UK "Liked the fact the speakers were available to answer questions during the coffee time. It was useful having the companies give seminars as opposed to just having them at their stand"- Sarah Burl, Infant Immunology Group, Virology Department, MRC The Gambia "Thoroughly enjoyed the meeting last week - just such a shame that I could not stay for the whole day - but what I did hear was very interesting. I certainly will come to more of the events as some of the titles on the programme look really good" - Professor Diana Watt, Professor of Human Anatomy, Brighton and Sussex Medical School, UK "We enjoyed the day very much indeed and look forward to attending another event soon".- Scott Reid. IAH Pirbright, Institute for Animal Health "Good location, staff very helpful, Tony Warford entertaining and knowledgeable chairman" - Pauline Connor, North Middlesex Hospital , London "Thank you for organising such a useful meeting. I know that it was apprecaited by many colleagues and that it provoked good discussion and scientific debate" - Dr Paul Duprex, School of Biomedical Sciences, The Queen's University of Belfast, Ireland "Well organised, interesting speakers were chosen" - Philippa Roddam, St Jude Children's Research Hospital , Memphis, USA "Very high quality talks and speakers"- Joanna Bridger PhD, Senior L ec turer, Centre for Cell and Chromosome Biology, Biosciences, Brunel University "I enjoyed the meeting, the duration of each of the speakers was just right and was pitched at just the right level for the audience. Great forum for meeting people and discussing the subject matter, overall very informative" - Vivien Jacobs, AstraZenea "I have found the talks very stimulating. The content was of high standard . A well run and presented meeting ".- Mrs Jean Bettany, Smith & Nephew, UK "Good range of talks – very interesting and relevant" - Dr Lorna Jarvis , Addenbrooke's Hospital, Cambridge, UK "James was pleased and said the meeting was excellent, with lots of discussion. I would be delighted to participate in the next edition". - Lorenzo Frigerio, Department of Biological Sciences, University of Warwick "Thank you very much for the invitation to speak last Friday. I found the meeting interesting, useful and enjoyable. Well done to the organisers". Paula Murphy B. A .(mod), PhD., Lecturer, Zoology Department, Trinity College Dublin, Ireland " Very much enjoyed the event - would definitely speak at a future EuroSciCon event if asked again". Chris Mason MB BS, PhD FRCS, Regenerative Medicine Bioprocessing Uni, Advanced Centre for Biochemical Engineering, University College, London " It was an enjoyable meeting, and as someone starting out in the proteomics field on a new collaborative grant very informative" . Peter J Charles, Chief Biomedical Scientist, Division of Immunology, Hammersmith Hospitals NHS Trust "The very informal setting enabled lively discussion in refreshment breaks" - Louise Jopling, UCB Group "Very well organised, friendly staff, good quality talks" - Professor John A Bryant, Chair, Christians in Science, School of Biosciences, University of Exeter "The event was very enjoyable and interesting. There was enough time for discussions after talks and during coffee/lunch breaks". - Swanand Gore "I found the meeting 'Visualising transcription, gene positioning and reorganisation in the nucleus' very very interesting. I'll keep into real consideration to came back to your next meetings" - Dr. MariaPaola Recalcati, Istituto A uxologico Italiano, Milan, Italy 'It was a very good meeting for Guava and I look forward to joining a few more in the future'. - Dr Paul Wheeler, UK Sales Manager, Guava Technologies Inc. "It is good to go to a relatively small meeting that is easy to go to and is good value for money. I think the mix between industry and academics is very good". - Prof W Ollier, Manchester University, CIGMR "A good selection of speakers and interesting subject matter " - Andrew Jefferson, Molec ular Cytogenetics and Microscopy, Wellcome Trust Center for Human Genetics, UK
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