Cytokine Event 2009

 

The meeting will be held at The BioPark, Hertfordshire, UK  and has CPD approval.
The Chair: will be Dr Stephen Thompson, (King's College London, UK)

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The deadline for EARLY REGISTRATION is 20th April 2009.  After this time fees will double.


 This meeting will have a  troubleshooting panel session. 
On registration you will be able to submit your questions to the panel that will be asked by the chair on the day of the event

 

The Agenda includes:

 

Cytokine detection in collagen-induced arthritis. Dr Richard Williams, Kennedy Institute of Rheumatology Division, Imperial College, UK.

Collagen-induced arthritis is a model of rheumatoid arthritis that has been used extensively to validate novel therapeutic targets. The main pathological features of the disease include synovitis, pannus formation and joint erosion. There is a great deal of interest in the development and testing of drugs with the capacity to modulate inflammatory pathways in arthritis. Hence, there is a need to monitor the effect of novel treatments on cytokine expression in vivo. This presentation will focus on the techniques used to quantify changes in cytokine expression following therapeutic intervention .
 
Using ELIspot to detect rare antigen specific T cells . Dr Tim Tree, Kings College, London
 
Dissecting regulatory and effector responses using cytokine secretion assay and artificial antigens.
Dr John Campell – Miltenyi Biotec Ltd, Surrey, UK
 
IL-10, regulatory T cells and respiratory health: the role of the vitamin D pathway.
Dr Catherine Hawrylowicz, Kings College, London
 

 

Application of cytokines assays in the biotechnology sector - from proof-of-principle to clinical trials.
Dr  James N Francis, Senior Vaccine Development Scientist, Immune Targeting Systems Ltd, London, UK 

 

Talk title to be confirmed.  Dr. Deborah A. O'Neil, NovaBiotics Ltd, Aberdeen, UK  


Immunohistochemical visualization of cytokines and other small molecules. Dr Chris van der Loos, Academic Medical Center, Univ. of Amsterdam , The Netherlands .

The use of post-fixed cryostat tissue sections has been widely accepted as ‘gold-standard’ for testing primary antibodies in immunohistochemistry (IHC). However, IHC staining of unbound small molecules like cytokines, may result into false-positive plasma cells, whereas specific staining is lacking. Leaking of the cytokine molecule during post-fixation is most likely the cause of this problem. In contrast, pre-fixation does retain the small molecules much better. Based on these findings suggestions are made for positive controls from cells and the use of optimally formalin-fixed paraffin tissue sections. Furthermore, testing of more than one primary antibody is highly recommended. 
 
Differing multiplex cytokine analysis platforms . Dr Gendie Lash, Institute of Cellular Medicine, Newcastle. University.

Multiplex cytokine analysis technologies have become readily available in the last seven years.  Two main formats exist: multiplex sandwich ELISA and bead based assays.  While these have each been compared to individual ELISAs, there has been little direct comparison between the two formats.  I will discuss the comparison between two multiplex sandwich ELISA assays (FAST Quant and SearchLight) and a bead based assay (UpState Luminex). 


The deadline for early registration is April 20th 2009. After this time the fees will double, so make sure you register early!

 

 

Before the early registration deadline

After the early registration deadline

Standard

 £249+ VAT

 £485 + VAT

Academic

 £149 + VAT

 £298 + VAT

Student

£99 + VAT

£198 + VAT 

IBMS

 £149 + VAT

 £298 + VAT 


We invite abstract submissions.  A prize of a year’s subscription to Nature Reviews Immunology at the conclusion of the day will be awarded to the best oral/poster presentation. We encourage you to submit abstracts for these sessions, which are designed to promote a balanced program of talks, delivered by both well-established, pre-eminent researchers in the field as well as those starting out on their careers.
The deadline for abstract submission is April 10th. 
If you would like to book a place please visit : www.regonline.co.uk/cytokines09


 
If you book this event you will get 30% off the EARLY REGISTRATION FEE for registration to the partner ELISPOT FOLLOW UP EVENT  which will take place on the 15th Oct 2009. To find out more about this meeting go to www.regonline.co.uk/elispot09. On registering  for Efficient cytokine detection: The Way Forward you will receive an email giving you details of how to receive your discount to the October  ELISPOT event. 

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