www.regonline.co.uk/innate2014
This event has an open poster session. Posters can be submitted on any subject related to Innate Immunity
A three day event discussing aspects of the innate immune system.
This year there are three main topics for discussion
- The Innate Immunity Interactions with Pathogens
- Interactions of the Innate and Adaptive Immune Systems
- Therapeutic applications of the Innate Immune system
With plenty of opportunity for networking and debate, this informal international meeting will bring you up to date with current research and thinking regarding an organisms first line of defense.
Infectious disease are still a major cause of morbidity and mortality worldwide. Innate immunity is of paramount importance for the control of pathogens in the early stages of the infection and for the engenderment and expansion of acquired immunity. This will be a premier forum for the presentation of cutting-edge research on how the interaction between innate immune mechanisms and pathogens impacts on host resistance, immunoevasion, immunodeficiencies and vaccine efficacy, providing
a deep insight into future research and more rational measures to prevent and treat infectious diseases of humans and animals. Session Chair: Dr Pietro Mastroeni, Cambridge University, UK
Day 2: Investigating interactions of the Innate and Adaptive Immune Systems
The cells of the innate immune system play a crucial part in immune defense against disease but also respond to the presence of malignant cells, initiating and subsequently directing adaptive immune responses. The session will discuss the roles of different components of the innate immune system, with focus on disease mechanisms and interactions between inflammatory cells, antibodies and pathogenic or tumour antigens and how these impact on disease progression. The session will draw on new cutting edge research and will provide ample opportunity for networking and informal discussions.
Session Chair: Dr Sophia N. Karagiannis, Senior Lecturer in Translational Cancer Immunology, Head of Cancer Antibody Discovery and Immunotherapy, St John’s Institute of Dermatology, Division of Genetics and Molecular Medicine, King’s College London School of Medicine, UK
Day 3: Therapeutic applications of the Innate Immune system
The identification of antigen recognition receptors for innate immunity has sparked great interest in therapeutic manipulation of the innate immune system. For example Toll-like receptor agonists are being developed for the treatment of cancer, allergies and viral infections, and as adjuvants for cancer and disease vaccines. This session will explore current research and applications of the innate system for therapeutic applications. There will be plenty of opportunity for discussion and debate and we encourage submission of abstracts for both oral and poster presentation. Session Chair: To be confirmed
Talks Include:
Exploring pathogen recognition in innate immunity using Drosophila as a model host
Dr Petros Ligoxygakis, Lecturer of Genetics, University of Oxford, UK
Is Immune Activation Necessary for HIV
Professor Wenzhe Ho, Dept. Pathology & Laboratory Medicine Dept. Anatomy & Cell Biology, Temple University School of Medicine, USA
Non-specific Stressors: Under-appreciated Innate Defenses
Dr Edmund LeGrand, Adjunct professor , Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN, USA
Understanding the roles of innate and adaptive immunity in the mechanisms of action of immunomodulatory antibodies.
Dr Stephen A Beers, Antibody and Vaccine Group, Faculty of Medicine, University of Southampton, UK
HPV and innate immunity
Dr Uzma Hasan, Oncoviruses and Innate Immunity Centre International de Recherche en Infectiologie, University Lyon, Hopital Lyon Sud, France
TRIF-mediated TLR3 and TLR4 signaling is negatively regulated by ADAM15
Dr Sinead Miggin, Lecturer and Principal Investigator, National University of Ireland Maynooth, Ireland
Professor Jerry Wells, Host-Microbe Interactomics – Wageningen, The NetherlandsInteraction of HIV with plasmacytoid dendritic cells and its relevance for HIV pathogenesis
Dr Adriano Boasso, Principal Investigator – Research Fellow, Imperial College London, UK
Lipid rafts influence NLR mediated immune responses against bacterial infections
Dr Sanjay Batra, Assistant Professor, Louisiana State University, USA
Dr Elizabeth Brint, Lecturer and Principal Investigator,University College Cork, IrelandParamyxovirus Inhibition of Human Complement Pathways
Dr Pietro Mastroeni, Reader in Infection and Immunity, University of Cambridge, UKThe MHC class II-associated invariant chain controls innate and adaptive immunity in B cells
Dr Jim Faix, Director of Chemistry & Immunology, Director of Point-of-Care Testing, Department of Pathology, Stanford University Medical Center, Stanford, USA
Intranasal vasoactive intestinal polypeptide (VIP) safely corrects multiple abnormalities in proteomics of innate immune responses and simultaneously restores regulation to differential genomic activation and suppression
Dr Przemyslaw Blyszczuk, Junior Group Leader, Cardioimmunology, University of Zurich, Switzerland
High-intensity ultra-short electric pulse applications in modulating innate immunity
Dr Charles Mills, BioMedical Consultants, United StatesInflammatory networks controlling cancer metastatic dissemination
Dr Victoria Sanz-Moreno, PhD, Cancer Research UK Career Development Fellow, Head of the Tumour Plasticity lab, Randall Division of Cell and Molecular Biophysics, New Hunt’s House, Guy’s Campus, King’s College, London SE11UL, United KingdomObesity and the skeleton
Professor Juliet Compston, University of Cambridge, UK
Speakers Include:
Dr Sema Becerik, Ege University, Turkey
Dr Claudia Monaco, Imperial College London, United Kingdom
Dr Hans U. Lutz, Institute of Biochemistry, Swiss Federal Institute of Technology, Switzerland
